In the Katawa Shoujo fic Lilly Epilogue: Family Matters, Lilly's father is this, even apart from the canonical Parental Abandonment inflicted on Lilly and Akira for six years. He is incredibly condescending to Hisao and Hanako, referring to them impersonally and making fun of their disabilities. In Hanako's case, he mocks her timidity and asks if she got her burn scars from catching the oven on fire; considering he was warned in advance and the real reason she got them, this is a borderline Moral Event Horizon. He does apologize to Lilly and accept Hisao in the end, though.
Ronan in Naruto Veangance Revelaitons, in so many ways. He's typically quite arrogant, even towards those he doesn't hold in contempt, and frequently insults his girlfriends and other friends. He also enjoys Disproportionate Retribution, and will kill people who try to stop him from stealing things. The author tried to make Edfred this, but it failed; he's quite popular for standing up to Ronan.
On the Big Bad Ensemble side, Shingetsu is the result of taking Social Darwinism to high levels of extremes. In general, Shingetsu is a Misanthrope SupremeBlood Knight who doesn't seem to care about his minions being used as cannon fodder, and has an utter disregard for human lives even when said human is subjected to experimentation by an opposing villainous faction.