Also, Kent Mansley saying "Screw the Country! I Wanna Live" as his final lines in the movie after he unwittingly sent a nuke directly into the town becomes extremely ironic when the President in Shadow the Hedgehog (who is strongly implied to be the same president from Sonic Adventure 2) is redesigned to resemble Kent Mansley.
Memetic Mutation: Dean's facial expressions are remarkably well-animated, such that he's become a source for reaction images on certain parts of 4chan.
Watch the scene where Dean "meets" Hogarth's squirrel. Starting from the time when he says "CALLMEDEAN," frame by frame it. Tell me you don't laugh your ass off at every single facial expression he makes.
Vindicated by History: The film was praised by critics, but that didn't save the film from a horrible fate at the box office; Warner Bros.' marketing blitz for the home video release (as well as Cartoon Network airing the film numerous times in the past few years) led to the film being seen by a wider audience, and now it's considered a modern animation classic.
Cartoon Network once did a Memorial Day special of airing the movie over and over and over and over and over again back-to-back, three days in a row.